Adult-onset familial laryngeal abductor paralysis, cerebellar ataxia, and pure motor neuropathy
- 22 May 2001
- journal article
- case report
- Published by Wolters Kluwer Health in Neurology
- Vol. 56 (10), 1412-1414
- https://doi.org/10.1212/wnl.56.10.1412
Abstract
Two brothers presented with late-onset cerebellar ataxia and severe dysphonia. Brain MRI showed vermian and hemispheric cerebellar atrophy. Laringofiberscopy revealed laryngeal abductor paralysis in both patients. Neurophysiologic studies showed a pure motor neuropathy. The combined findings and the molecular analysis suggest a new familial disorder. Inheritance is most likely autosomal recessive, but X-linked transmission is also possible.Keywords
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