Kainic Acid Injections Result in Degeneration of Cochlear Nucleus Cells Innervated by the Auditory Nerve
- 8 December 1978
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 202 (4372), 1087-1089
- https://doi.org/10.1126/science.31000
Abstract
When kainic acid, a putative neurotoxin for neurons with glutamatergic input, is injected into the brainstem, it produces a selective pattern of degeneration in the cochlear nucleus. The rate and extent of degeneration is correlated with the distribution of the primary auditory fibers. This evidence supports the hypothesis that glutamate is the neurotransmitter for primary auditory fibers.This publication has 13 references indexed in Scilit:
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