An Evaluation of the Influence of DL-Methionine Treatment on the Serum Lipids of Adult American Males

Abstract

STUDIES with monkeys have revealed that hypercholesterolemia and subsequent vascular lesions are produced in this primate species if the animals are given a diet deficient in the sulfur-containing amino acids cystine and methionine and at the same time receive large amounts of cholesterol in the diet.¹ Also in this species, as well as in rats and mice, either dietary supplements of cystine or methionine or protein rich in these amino acids will largely prevent the anticipated hypercholesterolemia and will reverse the existing abnormality produced by such procedures.² The data of dietary surveys done by two groups of workers indicate that . . .