Second Primary Cancer after Irradiation of Laryngeal Cancer
- 1 November 1975
- journal article
- Published by SAGE Publications in Annals of Otology, Rhinology & Laryngology
- Vol. 84 (6), 771-775
- https://doi.org/10.1177/000348947508400607
Abstract
Thirty (5.6%) of 535 patients followed 5–25 years after treatment of cordal carcinoma (T1A,B) developed a second primary laryngeal carcinoma. When analyzed by treatment modality, 3.9% of operated cases and 9% of irradiated cases formed new laryngeal or laryngopharyngeal malignancies. An explanation by radiation-induced carcinogenesis for this statistically significant difference between the two groups is discussed. It is also suggested that supervoltage radiation directed to the laryngeal mucosa may produce the diminished latent period observed between the appearance of the second primary carcinoma.Keywords
This publication has 13 references indexed in Scilit:
- Radiation induced cancer of larynx and pharynxThe Journal of Laryngology & Otology, 1971
- XCIV Juvenile Laryngeal PapillomatosisAnnals of Otology, Rhinology & Laryngology, 1965
- Carcinoma of the thyroid and laryngopharynx following irradiation.A report of 3 casesCancer, 1965
- Skin and Neck Cancer Following Radiation Therapy for Benign DiseasesThe Tohoku Journal of Experimental Medicine, 1965
- The Cancerogenic Effect of X-Ray on the LarynxJAMA Otolaryngology–Head & Neck Surgery, 1962
- XXXIV Pseudosarcoma of the Pharynx and LarynxAnnals of Otology, Rhinology & Laryngology, 1959
- Radiation Cancer. A Review with Special Reference to Radiation Tumours in the Pharynx, Larynx, and ThyroidThe British Journal of Radiology, 1957
- Pseudosarcoma (polypoid sarcoma-like masses) associated with squamous-cell carcinoma of the mouth, fauces, and larynx.Report of ten casesCancer, 1957
- POSTCRICOID CARCINOMA AS A SEQUEL TO RADIOTHERAPY FOR LARYNGEAL CARCINOMAJAMA Otolaryngology–Head & Neck Surgery, 1955
- Radiation Cancer of the PharynxBMJ, 1951