Inositol 1,3,4,5-tetrakisphosphate causes release of Ca2+ from permeabilized mouse lymphoma L1210 cells by its conversion into inositol 1,4,5-trisphosphate
- 1 May 1989
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 259 (3), 931-933
- https://doi.org/10.1042/bj2590931
Abstract
Addition of Ins(1,3,4,5)P4 at micromolar concentrations cause release of Ca2+ from electroporated L1210 cells, but not from digitonin-permeabilized cells. This was shown to be due to its conversion into Ins(1,4,5)P3, because only the electroporated cells convert Ins(1,3,4,5)P4 into Ins(1,4,5)P3. Thus electroporation appears to activate or expose an Ins(1,3,4,5)P4 3-phosphatase.This publication has 10 references indexed in Scilit:
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