Histocompatibility antigens in progressive systemic sclerosis (PSS; scleroderma)
- 1 October 1982
- journal article
- research article
- Published by Springer Nature in Journal of Clinical Immunology
- Vol. 2 (4), 314-318
- https://doi.org/10.1007/bf00915073
Abstract
Patients with progressive systemic sclerosis (PSS; scleroderma) were typed for the HLA-A, -B, and -DR antigens. No significant differences in the frequencies of any HLA-A or -B antigen were found. In the subgroup of patients with PSS and diffuse scleroderma (PSS-DS), the frequency of Bw35 was increased (0.30 vs 0.17 in controls;P0.2). Although patients with PSS-DS also had an increased frequency of DR1 antigen (0.27 vs 0.12 in local controls;PPPP<0.005). This study of a large number of patients with PSS failed to confirm previously reported associations of PSS with the HLA-B8/DR3 haplotype or HLA-DR5 antigen.Keywords
This publication has 22 references indexed in Scilit:
- INCREASED PREVALENCE OF DRw3 IN THE CREST SYNDROMEArthritis & Rheumatism, 1981
- HLA-D Antigens in Progressive Systemic Sclerosis (Scleroderma)Immunological Communications, 1981
- Preliminary criteria for the classification of systemic sclerosis (scleroderma)Arthritis & Rheumatism, 1980
- HLA‐B8 in Raynaud's PhenomenonTissue Antigens, 1980
- HLA and SclerodermaTissue Antigens, 1979
- Association of the B-Cell Alloantigen DRw4 with Rheumatoid ArthritisNew England Journal of Medicine, 1978
- Association of HLA Antigen A9 with Progressive Systemic Sclerosis (Scleroderma)Tissue Antigens, 1978
- HLA-Antigenfrequenzen bei Patienten mit progressiver Sklerodermie und MorphaeaArchives of Dermatological Research, 1978
- Sjögren's Syndrome in Progressive Systemic SclerosisAnnals of Internal Medicine, 1977
- Simultaneous detection of two cell populations by two-colour fluorescence and application to the recognition of B-cell determinantsNature, 1976