KWASHIORKOR TYPE OF FATTY LIVER IN PRIMATES
Open Access
- 1 September 1958
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 108 (3), 361-370
- https://doi.org/10.1084/jem.108.3.361
Abstract
Fatty livers resembling those seen in the early stages of kwashiorkor were produced in primates. Monkeys were fed, for about 1 year, purified diets free from choline and betaine and low in methionine. Supplementation with choline slightly improved food consumption and gain in weight. Choline prevented the appearance of any stainable lipid in the liver of the control animals. The extent to which the slightly greater intake of protein, including methionine, in the choline-supplemented animals contributed to the prevention of the periportal accumulation of fat in the liver is being determined.Keywords
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