Relationship between the enhanced expression of histocompatibility antigens on interferon‐treated L 1210 cells and their position in the cell cycle
- 1 January 1976
- journal article
- research article
- Published by Wiley in European Journal of Immunology
- Vol. 6 (1), 56-59
- https://doi.org/10.1002/eji.1830060112
Abstract
We have determined the cell cycle position of individual mouse leukemia L 1210 cells by cytophotometric and autoradiographic techniques and simultaneously determined the amount of histocompatibility antigens expressed on the surface of individual cells by quantitative immunofluorescence. Interferon treatment of L 1210 cells was accompanied by an enhanced expression of histocompatibility surface antigens. The distribution of interferon-treated cells in the various phases of the cell cycle was similar to that for control cells and the enhanced expression of histocompatibility antigens was observed on interferon-treated cells in all phases of the cell cycle. We conclude, therefore, that this enhancement is not due to a preferential concentration of these cells in any one particular phase of the cell cycle.This publication has 11 references indexed in Scilit:
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