MONOAMINE-OXIDASE INHIBITORS AND TRICYCLIC ANTIDEPRESSANTS - COMPARISON OF THEIR CARDIOVASCULAR EFFECTS
- 1 May 1986
- journal article
- research article
- Vol. 47 (5), 225-229
Abstract
The cardiovascular effects of monoamine oxidase inhibitors (MAOIs) are contrasted with those of the tricyclic antidepressants (TCAs). At therapeutic doses, MAOIs lower supine blood pressure and increase the postural fall in blood pressure, whereas TCAs have only the latter effect. MAOIs have little effect on heart rate and do not prolong cardiac conduction; TCAs increase heart rate and prolong cardiac conduction. Neither class of drugs appears to impair cardiac mechanical functioning. For patients with certain cardiac problems, MAOIs may have an advantage over TCAs.This publication has 14 references indexed in Scilit:
- CARDIAC AND RENAL HEMODYNAMIC RESPONSE TO PARGYLINEAnnals of the New York Academy of Sciences, 2006
- Cardiovascular Effects of Tricyclic Antidepressants in Depressed Patients with Chronic Heart DiseaseNew England Journal of Medicine, 1982
- CARDIOVASCULAR EFFECTS OF PHENELZINE AND AMITRIPTYLINE IN DEPRESSED OUTPATIENTS1982
- Phenelzine and Amitriptyline in the Treatment of DepressionArchives of General Psychiatry, 1980
- CLINICAL CHARACTERISTICS OF IMIPRAMINE-INDUCED ORTHOSTATIC HYPOTENSIONThe Lancet, 1979
- Cardiac Antiarrhythmic Effect of Imipramine HydrochlorideNew England Journal of Medicine, 1977
- MECHANISM OF ACTION OF MONOAMINE OXIDASE INHIBITORS IN EXPERIMENTAL MYOCARDIAL INFARCTION IN THE PIGAnnals of the New York Academy of Sciences, 1963
- ECTOPIC VENTRICULAR RHYTHMS AND MYOCARDIAL INFARCTION IN THE DOMESTIC PIG AND THEIR RESPONSE TO NIALAMIDE, A MONOAMINE OXIDASE INHIBITORBritish Journal of Pharmacology and Chemotherapy, 1962
- CARDIAC ACTIVITIES OF SEVERAL MONOAMINE OXIDASE INHIBITORS1961
- The application of a monoamine-oxidase inhibitor, 1-phenyl-2-hydrazinopropane (JB-516), to the treatment of primary hypertensionAmerican Heart Journal, 1959