Carcinoma of the prostate gland is a common and lethal disease. For many years, urologists have attempted to establish an early diagnosis of the disease at a time when the nodular growth is entirely confined within the prostate gland, and have advocated complete extirpation of the growth by radical prostatectomy. Jewett et al35have recently published data emphasizing the wisdom of this radical approach to carcinoma of the prostate and report that of 86 patients followed up for 15 or more years after radical perineal prostatectomy, 33% (28) are living without evidence of cancer. The dramatic regression of primary carcinomatous lesions of the prostate which often results from endocrine-control therapy suggested to a number of urologists36-40that radical perineal prostatectomy might prove curative for selected patients whose carcinomatous lesions were too far advanced to permit radical prostatectomy when first examined. Our experience in treating these advanced cases of