Confidence limits for estimates of gene linkage based on analysis of recombinant inbred strains
- 1 November 1985
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Heredity
- Vol. 76 (6), 436-440
- https://doi.org/10.1093/oxfordjournals.jhered.a110140
Abstract
Recombinant inbred (RI) strains are extremely useful for genetic mapping. This paper presents a simple method for determining confidence intervals for linkage estimates based on analysis of RI strains. The results show that such confidence intervals are usually large with the currently available numbers of RI strains. Therefore, map positions based only on analysis of RI strains should be interpreted with caution. To facilitate interpretation of linkage data derived from RI strains, a table is presented giving the 95 percent and 99 percent confidence intervals for all possible linkages detected with up to 45 RI strains.This publication has 2 references indexed in Scilit:
- RECOMBINANT INBRED STRAINS: USE IN GENE MAPPINGPublished by Elsevier ,1978
- Inbreeding and linkage1931