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The p53 paddy wagon: COP1, Pirh2, and MDM2 are found resisting apoptosis and growth arrest
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The p53 paddy wagon: COP1, Pirh2, and MDM2 are found resisting apoptosis and growth arrest
The p53 paddy wagon: COP1, Pirh2, and MDM2 are found resisting apoptosis and growth arrest
CC
Chad A. Corcoran
Chad A. Corcoran
YH
Ying Huang
Ying Huang
M. Saeed Sheikh
M. Saeed Sheikh
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1 August 2004
journal article
Published by
Taylor & Francis
in
Cancer Biology & Therapy
Vol. 3
(8)
,
721-725
https://doi.org/10.4161/cbt.3.8.1068
Abstract
For years, the growth inhibitory effects of the tumor suppressor p53 were thought to be antagonized predominantly by the ubiquitin ligase, MDM2. It has long been established that MDM2 physically as...
Keywords
APOPTOSIS
FUNCTION
MDM2
PROTEINS
SUPPRESSOR
P53
STRESS
UBIQUITIN
LIGASE
PROTEASOME
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Open Access
Cited by 35 articles