PRENATAL CLOSURE OF THE INTERATRIAL FORAMEN
- 1 March 1953
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Pediatrics & Adolescent Medicine
- Vol. 85 (3), 285-294
- https://doi.org/10.1001/archpedi.1953.02050070295003
Abstract
THE ABSENCE of an interatrial communication before birth causes distortions in cardiac development which render the heart incapable of proper function after birth. Patten1 has called attention to the fact that the foramen ovale normally transmits at least half of the blood that enters the left side of the fetal heart. Premature closure of the foramen, therefore, deprives the left atrium and ventricle of all blood from the systemic and placental circulations. Only the pulmonary circulation, which in the fetus is of relatively small quantity, empties into the left atrium. Since this is not sufficient to bring about normal expansion and muscular development of the left-sided chambers, they become hypoplastic, whereas the right-sided chambers tend to become distended and hypertrophied. The right ventricle during fetal life must assume the entire burden of pumping blood through the systemic circulation by way of the ductus arteriosus. These conditions may be toleratedKeywords
This publication has 3 references indexed in Scilit:
- ABSENCE OF THE LEFT CARDIAC VENTRICLE WITH APLASIA OF THE AORTIC ORIFICE AND HYPOPLASIA OF THE AORTA1946
- Premature closure of the foramen ovaleAmerican Heart Journal, 1939
- Cor biatriatum triloculareAmerican Heart Journal, 1926