Studies on the Free Amino Acids and Related Compounds in the Brains of Fish, Amphibia, Reptile, Aves and Mammal by ion Exchange Chromatography

Abstract

The present study has been undertaken to detect whether there exists any difference in the free amino acids and their related compounds in the brains of the various classified animals. The analysis of the free amino acids in the brains of several mammal species have so far been reported by many authors (1–6). These data were obtained chiefly by paperchromatographic procedure. The method is convenient, but is not exact in the quantitative analysis. Some of these data were obtained by the microbiological method (2, 7, 8). More satisfactory results were obtained, however, by using ion-exchange chromatographies (9–11). In the present study, a significant difference in the distribution patterns of free amino acids and their related compounds in the brains of various animals of the vertebrate was found by means of ion-exchange chromatographic procedures.