?-Cyanation of Tertiary Amines
- 1 January 1980
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 10 (7), 495-502
- https://doi.org/10.1080/00397918008069324
Abstract
The α-cyanation of tertiary amines is customarily accomplished by mercuric acetate oxidation of the amine to form the enamine, which on treatment with base yields the corresponding Schiff's base. Subsequent treatment with aqueous potassium cyanide yields the desired product2. Alternatively, and less commonly, the α-cyanation of tertiary amines can be carried out electrolytically3,4Keywords
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