Hypogonadism Associated with Chromosomal Break in Autosome No. 2 and Translocation Presumably on the Y Chromosome

Abstract

Hypogonadism of testicular origin in a 47-yr.-old patient was found to be associated with a break of the short arms of autosome No. 2, and translocation on a small acrocentric chromosome, believed to be the Y chromosome. The possibility that this unusual chromosomal pattern is the cause of the hypogonadism is discussed.