L-Cysteine Modified Silver Electrode and Its Application to the Study of the Electrochemistry of Hemoglobin
- 1 June 1996
- journal article
- chemical and-bio-sensors
- Published by Taylor & Francis in Analytical Letters
- Vol. 29 (8), 1273-1280
- https://doi.org/10.1080/00032719608001480
Abstract
L-cysteine can be modified onto a silver electrode by covalent binding through the sulphur to give very stable and long-lived chemically modified electrodes(CMEs). Hemoglobin(Hb) exhibits an excellent voltammetric response at the resulting CMEs. Linear sweep voltammetric(LSV) measurements of Hb on the CMEs reveal the existence of a linear relationship between the cathodic peak current and the concentration of Hb in the range of 5 X 10−7 - 1 X 10−5 mol/L. The detection limit is about 2 X 10−7 mol/L. The relative standard deviation of results is 4.5% for 10 successive determinations at 2 X 10−6 mol/L. Other proteins and chemicals present in samples do not interfere in the assay.Keywords
This publication has 7 references indexed in Scilit:
- Methylene Blue/Perfluorosulfonated Ionomer Modified Microcylinder Carbon Fiber Electrode and Its Application for the Determination of HemoglobinAnalytical Chemistry, 1994
- Dynamic Electrochemistry: Methodology and ApplicationAnalytical Chemistry, 1994
- Direct electron transfer reaction of hemoglobin at the bare silver electrodeJournal of Electroanalytical Chemistry, 1994
- SERS and XPS studies of the molecular orientation of thiophenols from the gaseous state onto silverJournal of Colloid and Interface Science, 1992
- Electron-transfer reaction of cytochrome c adsorbed on carboxylic acid terminated alkanethiol monolayer electrodesJournal of the American Chemical Society, 1991
- Catalytic reduction of myoglobin and hemoglobin at chemically modified electrodes containing methylene blueAnalytical Chemistry, 1988
- SERS application to some electroorganic reactionsSurface Science, 1985