Metabolism of Glycine.

Abstract

The metabolism of glycine in normal mice was studied after a single injn. of glycine-2-C14 by following the specific activity of the uncombined glycine in plasma, liver and muscle, as well as the specific activity of the respiratory CO2. The size of the dynamic body pool of glycine was 30 mg./100 g. of which 10 mg./100 g. was uncombined glycine; turnover time of the glycine pool was 1.5 hrs. and the rate of turnover 20 mg./100 g./ hr. Approx. 10 times as much glycine was oxidized to yield CO2 as was ingested in the food.