Opioid Therapy for Chronic Pain
Top Cited Papers
- 13 November 2003
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 349 (20), 1943-1953
- https://doi.org/10.1056/nejmra025411
Abstract
A difficult decision for physicians who treat patients with chronic pain not associated with terminal disease is whether and how to prescribe opioid therapy, which can relieve pain and improve mood and level of functioning in many such patients. This review considers current guidelines for opioid therapy in patients with chronic pain unrelated to malignant conditions and outlines caveats, areas of uncertainty, and management strategies.Keywords
This publication has 82 references indexed in Scilit:
- Efficacy and Safety of a Once-Daily Morphine Formulation in Chronic, Moderate-to-Severe Osteoarthritis Pain: Results from a Randomized, Placebo-Controlled, Double-Blind Trial and an Open-Label Extension TrialJournal of Pain and Symptom Management, 2002
- Efficacy of Analgesics in Chronic Pain: A Series of N-of-1 StudiesJournal of Pain and Symptom Management, 1998
- Long-term opioid therapy: Assessment of consequences and risksJournal of Pain and Symptom Management, 1996
- Oral methadone for managing chronic nonmalignant painJournal of Pain and Symptom Management, 1996
- Government regulatory influences on opioid prescribing and their impact on the treatment of pain of nonmalignant originJournal of Pain and Symptom Management, 1996
- Opioid therapy for chronic nonmalignant pain: a review of the critical issuesJournal of Pain and Symptom Management, 1996
- Side effects of intrathecal and epidural opioidsCanadian Journal of Anesthesia/Journal canadien d'anesthésie, 1995
- Cold-pressor pain tolerance in opiate and cocaine abusers: Correlates of drug type and use statusJournal of Pain and Symptom Management, 1994
- Long-term use of opioid analgesics for the treatment of chronic pain of nonmalignant originJournal of Pain and Symptom Management, 1993
- Long-term oral opioid therapy in patients with chronic nonmalignant painJournal of Pain and Symptom Management, 1992