Structure of Fischerin, a New Toxic Metabolite from an Ascomycete, Neosartorya fischeri var. fischeri

Abstract

A new toxic metabolite named fischerin [1] from an Ascomycete. Neosartorya fischeri var. fischeri, which caused lethal peritonitis in mice, was deduced to have a structure including a 1,4-dihydroxy-3,5-disubstituted-2(1H)-pyridone moiety by chemical and spectral data.