Abstract
Using the nephrostome of the kidney of living Necturi for introducing the dye, chiefly tetrachlorphenolsulphonephthalein, into the lumen of the renal tubule, direct microscopic observation showed that no appreciable amount was absorbed by the renal cells from the lumen of the tubule in intervals as long as 2 hrs. from the time of intraperitoneal injection of the dye. Intravascular injections of the same dye, however, following the intraperitoneal, resulted in coloration of the cells of the proximal convoluted tubule within 15 min. or more.