Human c-fms proto-oncogene: comparative analysis with an abnormal allele.
Open Access
- 1 February 1985
- journal article
- Published by Taylor & Francis in Molecular and Cellular Biology
- Vol. 5 (2), 422-426
- https://doi.org/10.1128/mcb.5.2.422
Abstract
The organization of the human c-fms proto-oncogene has been determined and compared with an abnormal allele. The human v-fms homologous genetic sequences are dispersed discontinuously and colinearly with the viral oncogene over a DNA region of ca. 32 kilobase pairs. The abnormal c-fms locus contains a small deletion in its 3' portion. DNA sequencing analysis indicated that it was 426 base pairs in size and located in close proximity to a putative c-fms exon.Keywords
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