Donor-to-Host Transmitted Candida Endophthalmitis After Penetrating Keratoplasty
- 1 October 2005
- journal article
- case report
- Published by Wolters Kluwer Health in Cornea
- Vol. 24 (7), 887-889
- https://doi.org/10.1097/01.ico.0000157403.27150.c1
Abstract
To report the first case of Candida albicans endophthalmitis following penetrating keratoplasty after warm preservation. Observational case report. We reviewed the patient's chart and the available literature on fungal endophthalmitis after keratoplasty. After keratoplasty, a 45-year-old man developed an endophthalmitis on the first postoperative day. The same day, results of the culture of the transportation medium were available and revealed Candida albicans. Despite therapy with topical and subtenon amphotericin B, there was no clinical improvement, and a regraft was performed 4 days after the initial corneal transplant. A best corrected visual acuity of 20/32 was achieved. The majority of reported cases of postkeratoplasty candidal endophthalmitis are associated with cold storage preservation and a poor prognosis of the affected eye. We describe a case of postkeratoplasty candidal endophthalmitis after organ-cultured preservation, with a final visual acuity above expectations. In our opinion, early diagnosis based on routine culturing of the transportation medium and early removal of the infected corneal graft when local antifungal therapy failed are important factors contributing to the good clinical outcome.Keywords
This publication has 17 references indexed in Scilit:
- Candidal Endophthalmitis After KeratoplastyCornea, 2001
- Candida glabrata endophthalmitis following penetrating keratoplastyBritish Journal of Ophthalmology, 1998
- Bacterial and Fungal Endophthalmitis After Penetrating KeratoplastyAmerican Journal of Ophthalmology, 1993
- Candida tropicalis endophthalmitis following penetrating keratoplasty.British Journal of Ophthalmology, 1991
- Contamination of Donor Cornea: Postpenetrating Keratoplasty EndophthalmitisCornea, 1991
- Endophthalmitis From Contaminated Donor Corneas Following Penetrating KeratoplastyArchives of Ophthalmology (1950), 1991
- Corneo-scleral rim cultures: Donor contamination a case of fungal endophthalmitis transmitted by K-Sol stored corneaEye, 1988
- Candida albicans Endophthalmitis after Penetrating KeratoplastyAmerican Journal of Ophthalmology, 1987
- Candida albicans Endophthalmitis Following Penetrating KeratoplastyArchives of Ophthalmology (1950), 1987
- Torulopsis glabrata Endophthalmitis After Keratoplasty With an Organ-Cultured CorneaArchives of Ophthalmology (1950), 1978