Multidrug Resistance — A Sign of the Times

Abstract

Resistance to antibiotics is a problem that confronts all of us, thwarting treatment of inpatients and outpatients and compromising therapy for animals, fish, and agricultural crops.¹ The frequency of resistance in bacteria and the numbers of drugs to which they are resistant are increasing. Multidrug resistance marks this decade, as further evidenced by the report by Glynn et al. in this issue of the Journal of a strain of Salmonella enterica serotype typhimurium, known as definitive type 104 (DT104), in the United States that is resistant to five drugs.² Salmonella, normally harbored in animals, can cause infections in people. Although . . .