High-speed separations of DNA sequencing reactions by capillary electrophoresis
- 1 May 1990
- journal article
- research article
- Published by American Chemical Society (ACS) in Analytical Chemistry
- Vol. 62 (9), 900-903
- https://doi.org/10.1021/ac00208a003
Abstract
Fluorescently labeled DNA fragments generated in enzymatic sequencing reactions are rapidly separated by capillary gel electrophoresis and detected at attomole levels within the gel-filled capillary. The application of this technology to automated DNA sequence analysis may permit the development of a second generation automated sequencer capable of efficient and cost-effective sequence analysis on the genomic scale.This publication has 5 references indexed in Scilit:
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