A facile one-step synthesis of cysteinyldopas using mushroom tyrosinase
- 1 August 1977
- journal article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 33 (8), 1118-1119
- https://doi.org/10.1007/bf01946005
Abstract
A convenient one-step procedure, based upon the tyrosinase co-oxidation of dopa and cysteine, is reported for the synthesis of 5-S-cysteinyldopa (I) in 74% yield. Secondary products of the reaction turned out to be 2-S-cysteinyldopa (II, 14%), 2,5-S, S-dicysteinyldopa (IV, 5%), and the hitherto unknown 6-S-cysteinyldopa (III, ∼1%).Keywords
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