Functionalized Mesoporous Silicates for the Removal of Ruthenium from Reaction Mixtures
- 27 May 2006
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 8 (13), 2663-2666
- https://doi.org/10.1021/ol060389g
Abstract
The removal of residual ruthenium after olefin metathesis reactions and asymmetric hydrogenations has been described using amine-functionalized mesoporous silicates. Aminopropyltriethoxy silane-derivatized silicates were found to be the most effective. More than 99.99% of RuCl3 could be removed in a single treatment. Scavenging of Ru after metathesis reactions using a Grubbs generation 1 catalyst gave a product with concentrations of less than 10 μg/5 mg after two treatments with amine-modified silica. Most importantly, no chromatography was required.Keywords
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