Growth of Children with Thalassaemia: Effect of Different Transfusion Regimens
Open Access
- 1 August 1970
- journal article
- review article
- Published by BMJ in Archives of Disease in Childhood
- Vol. 45 (242), 502-505
- https://doi.org/10.1136/adc.45.242.502
Abstract
Growth was studied in 74 children with homozygous β-thalassaemia aged 1 to 11 years, treated with three different transfusion regimens. In group I (38 cases) haemoglobin levels were maintained above 8 g./100 ml.; in group II (14 cases), pretransfusion haemoglobin levels ranged between 6 and 8 g./100 ml.; in group III (22 children), pretransfusion haemoglobin levels were below 6 g./100 ml. Children in group I grew normally, both in weight and height; those in groups II and III were retarded, particularly those in group III. Frequent transfusions, in spite of their disadvantages, at present constitute the treatment of choice.Keywords
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