Ligand-Free Heck Reaction: Pd(OAc)2 as an Active Catalyst Revisited
- 16 August 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 68 (19), 7528-7531
- https://doi.org/10.1021/jo034646w
Abstract
Palladium acetate was shown to be an extremely active catalyst for the Heck reaction of aryl bromides. Both the base and the solvent were found to have a fundamental influence on the efficiency of the reaction, with K3PO4 and N,N-dimethylacetamide being the optimal base and solvent, respectively.Keywords
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