Short and Efficient Synthesis of Enantiomerically Pure 4-Substituted (1E,3E)-1[(R)-p-Tolylsulfinyl]-1,3-butadienes

Abstract

The title compounds were readily prepared in two steps by the condensation of (+)-methyl p-tolyl (R)-sulfoxide to α,β-unsaturated aldehydes followed by a one-pot dehydration of the resulting β-hydroxy sulfoxides.