THE DISTRIBUTION AND EXCRETION OF S35-LABELED SULFO-BROMOPHTHALEIN-SODIUM ADMINISTERED TO DOGS BY CONTINUOUS INFUSION 1

Abstract

Hepatic BSP uptake accounts for a very large proportion of administered dye and errors in calculations based on the assumption that all of the BSP leaves the circulation on passage through the liver are relatively small. Continued uptake of BSP by skeletal muscle constitutes the major site of sustained extrahepatic dye extraction.