Quantitative phase-contrast imaging of cells with phase-sensitive optical coherence microscopy
- 1 July 2004
- journal article
- Published by Optica Publishing Group in Optics Letters
- Vol. 29 (13), 1509-1511
- https://doi.org/10.1364/ol.29.001509
Abstract
We describe a method for en face phase-contrast imaging of cells with a fiber-based differential phase-contrast optical coherence microscopy system. Recorded en face images are quantitative phase-contrast maps of cells due to spatial variation of the refractive index and (or) thickness of various cellular components. Quantitative phase-contrast images of human epithelial cheek cells obtained with the fiber-based differential phase-contrast optical coherence microscopy system are presented.Keywords
This publication has 9 references indexed in Scilit:
- En face imaging of single cell layers by differential phase-contrast optical coherence microscopyOptics Letters, 2002
- Phase-sensitive frequency-multiplexed optical low-coherence reflectometeryOptics Communications, 2001
- Phase-dispersion optical tomographyOptics Letters, 2001
- Interferometric phase-dispersion microscopyOptics Letters, 2000
- Quantitative phase tomographyOptics Communications, 2000
- Optical low-coherence reflectometer for differential phase measurementOptics Letters, 2000
- Differential phase contrast in optical coherence tomography.Optics Letters, 1999
- Digital holography for quantitative phase-contrast imagingOptics Letters, 1999
- Reconstruction of optical pathlength distributions from images obtained by a wide‐field differential interference contrast microscopeJournal of Microscopy, 1997