A Synthetic Ionophore for Ca2+: Studies with Model and Biological Systems
- 3 March 2005
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 117 (3), 559-562
- https://doi.org/10.1111/j.1432-1033.1981.tb06373.x
Abstract
The relatively simple .beta.-diketone, 1,1,1,2,2,3,3-heptafluoro-7,7-dimethyloctane-4,6-dione, known as fod, will solvate Ca2+ ions in an organic phase. It will transport Ca2+ across phospholipid bilayers. It acts as predicted for a Ca2+-transporting ionophore in 2 biological systems: it will stimulate Ca2+-dependent K+ efflux from human red blood cells, and Ca2+-dependent histamine secretion from rat peritoneal mast cells.This publication has 19 references indexed in Scilit:
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