Justicisaponin-I, a New Triterpenoid Saponin from Justicia simplex

Abstract

A new triterpenoid saponin, named justicisaponin-I, has been isolated from Jussticia simplex D. DON. (Acanthaceae). It has been assigned oleanolic acid-3-O-β-D-glucopyranosyl-4′-O-ferulate structure (1) on the basis of chemical transformation and comprehensive spectral evidence. Justicisaponin-I has produced significant sperm acrosomal membrane stabilizing action and may prove to be a potent antifertility agent. 1 Part 4 in the series: Chemical constituents of Justicia. For Part 3 see ref. [12].