Life of Guinea Pig Circulating Erythrocyte and its Relation to Erythrocyte Population of Bone Marrow.

Abstract
Three male guinea pigs of mixed strain, and weighing approximately 400 g were given 0.75 μc of Fe59Cl3/g body weight and percentage of labeled cells appearing in blood was noted over 8 days. For the first 7 days there was a linear increase in percentage of labeled erythrocytes. On the assumption that this represents the normal rate of new red cell formation, it is calculated that the circulating red cell in the guinea pig has a life of 83 days.