Practical Synthesis of β-Acyl and β-Alkoxycarbonyl Heterocyclic Sulfones
- 2 March 2011
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 76 (7), 2269-2272
- https://doi.org/10.1021/jo102326p
Abstract
A short and efficient synthesis for β-acyl and β-alkoxycarbonyl heterocyclic sulfones containing benzothiazol (BT) and phenyltetrazol (PT) heterocyclic core is presented here. The method seems to be general and provides the desired C-nucleophiles in very good to excellent yields from readily available starting materials.Keywords
This publication has 23 references indexed in Scilit:
- Asymmetric Organocatalysis with SulfonesAngewandte Chemie International Edition, 2010
- Catalytic Asymmetric Mannich Reactions of SulfonylacetatesAngewandte Chemie International Edition, 2009
- α-Fluoro-α-nitro(phenylsulfonyl)methane as a fluoromethyl pronucleophile: Efficient stereoselective Michael addition to chalconesProceedings of the National Academy of Sciences, 2009
- Asymmetric Michael Addition Mediated by Novel Cinchona Alkaloid-Derived Bifunctional Catalysts Containing SulfonamidesOrganic Letters, 2008
- Enantioselective Organocatalytic Approach to the Synthesis of α,α-Disubstituted CyanosulfonesThe Journal of Organic Chemistry, 2008
- Catalytic Enantioselective Michael Addition of 1‐Fluorobis(phenylsulfonyl)methane to α,β‐Unsaturated Ketones Catalyzed by Cinchona AlkaloidsAngewandte Chemie International Edition, 2008
- Asymmetric Aminocatalysis—Gold Rush in Organic ChemistryAngewandte Chemie International Edition, 2008
- Asymmetric Organocatalysis: From Infancy to AdolescenceAngewandte Chemie International Edition, 2008
- Special issue ContentsMarine Chemistry, 2007
- Highly Enantioselective Direct Conjugate Addition of Ketones to Nitroalkenes Promoted by A Chiral Primary Amine−Thiourea CatalystJournal of the American Chemical Society, 2006