TRANSPLANTATION OF THE INTACT MAMMALIAN HEART

Abstract

The subject of transplantation of various tissues or organs is important, since great practical value might come from the development of a successful method. This applies particularly to the transplantation of an organ such as the kidney, whereby a normal organ might be exchanged for a diseased one. A comprehensive review of the subject of transplantation of tissue has been made recently by Loeb,¹ and we shall, therefore, mention only a few considerations which are pertinent to our report. Two methods have been used for the transplantation of tissue. The method usually employed both clinically and experimentally has been to excise a small section of tissue and to implant it in the desired situation, expecting it to obtain its own blood supply. The other method has been to transplant a whole organ, anastomosing its blood vessels to other suitable vessels. The latter method was made technically possible by the