Dihydroindenoisoquinolines function as prodrugs of indenoisoquinolines
- 2 June 2005
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 15 (11), 2795-2798
- https://doi.org/10.1016/j.bmcl.2005.03.101
Abstract
No abstract availableKeywords
This publication has 20 references indexed in Scilit:
- Design, Synthesis, and Biological Evaluation of Indenoisoquinoline Topoisomerase I Inhibitors Featuring Polyamine Side Chains on the Lactam NitrogenJournal of Medicinal Chemistry, 2003
- Design, Synthesis, and Biological Evaluation of Cytotoxic 11-Alkenylindenoisoquinoline Topoisomerase I Inhibitors and Indenoisoquinoline−Camptothecin HybridsJournal of Medicinal Chemistry, 2003
- Non-Camptothecin DNA Topoisomerase I Inhibitors in Cancer TherapyCurrent Topics in Medicinal Chemistry, 2003
- Synthesis of New Dihydroindeno[1,2-c]isoquinoline and Indenoisoquinolinium Chloride Topoisomerase I Inhibitors Having High in Vivo Anticancer Activity in the Hollow Fiber Animal ModelJournal of Medicinal Chemistry, 2001
- Synthesis of New Indeno[1,2-c]isoquinolines: Cytotoxic Non-Camptothecin Topoisomerase I InhibitorsJournal of Medicinal Chemistry, 2000
- Synthesis of Cytotoxic Indenoisoquinoline Topoisomerase I PoisonsJournal of Medicinal Chemistry, 1999
- Protein-Linked DNA Strand Breaks Induced by NSC 314622, a Novel Noncamptothecin Topoisomerase I PoisonPublished by American Society for Pharmacology & Experimental Therapeutics (ASPET) ,1998
- Pharmacokinetics and pharmacodynamics of topotecan given on a daily-times-five schedule in phase II clinical trials using a limited-sampling procedureCancer Chemotherapy and Pharmacology, 1996
- The structural basis of camptothecin interactions with human serum albumin: impact on drug stabilityJournal of Medicinal Chemistry, 1994
- Stereoselective oxidation by thionyl chloride leading to the indeno[1,2-c]isoquinoline systemThe Journal of Organic Chemistry, 1978