Territrems, tremorgenic mycotoxins of Aspergillus terreus

Abstract

The tremorgenic mycotoxins isolated from A. terreus were given the trivial names territrem A and territrem B instead of their previous designations of C1 and C2, respectively. High-resolution mass spectral data suggested the molecular formula of territrem A to be C28H30O9 and that of territrem B, C29H34O9. They were partially characterized by UV, IR, PMR and mass spectroscopy. The spectroscopic evidence indicated that their chemical structures were very similar. The procedures of purification were also revised for the complete separation of these 2 chemically related compounds.