Quantitative relationships between in vitro antibacterial activities of cephalosporins and their n-octanol/water partition coefficients
- 1 January 1987
- journal article
- research article
- Published by Elsevier in International Journal of Pharmaceutics
- Vol. 34 (3), 241-246
- https://doi.org/10.1016/0378-5173(87)90186-4
Abstract
No abstract availableKeywords
This publication has 21 references indexed in Scilit:
- Substituent effects in cephalosporins as assessed by molecular orbital calculations, nuclear magnetic resonance, and kineticsJournal of Medicinal Chemistry, 1983
- ?-Lactam ring stability and antibacterial potency: A novel eigenvalue problemInternational Journal of Quantum Chemistry, 1983
- Electronic structures of cephalosporins and penicillins. 11. Parabolic relationships between antibacterial activity of cephalosporins and .beta.-lactam reactivity predicted from molecular orbital calculationsJournal of the American Chemical Society, 1980
- Use of a Heavy Inoculum in the In Vitro Evaluation of the Anti-Staphylococcal Activity of 19 CephalosporinsAntimicrobial Agents and Chemotherapy, 1978
- In vitro studies with cefazaflur and other parenteral cephalosporins.The Journal of Antibiotics, 1977
- Hansch Analysis of Interaction of Haptens with Benzylpenicilloyl AntibodiesJournal of Pharmaceutical Sciences, 1975
- Influence of lipophilic character on the antibacterial activity of cephalosporins and penicillinsJournal of Medicinal Chemistry, 1970
- Correlation of serum binding of penicillins with partition coefficientsBiochemical Pharmacology, 1967
- The Structure-Activity Relationship in PenicillinsJournal of Medicinal Chemistry, 1965
- The Use of Substituent Constants in the Analysis of the Structure-Activity Relationship in Penicillin DerivativesJournal of Medicinal Chemistry, 1964