β-Carotene–vitamin A equivalence in Chinese adults assessed by an isotope dilution technique
Open Access
- 1 January 2004
- journal article
- Published by Cambridge University Press (CUP) in British Journal of Nutrition
- Vol. 91 (1), 121-131
- https://doi.org/10.1079/bjn20031030
Abstract
The present study was carried out to determine the conversion factor of synthetic 2H-labelled 60 years were recruited for a 55 d experiment. The volunteers (nine males and six females) were each given a physiological dose of [2H8]-Carotene and retinol were extracted from serum and isolated by HPLC, and their enrichments were respectively determined by using GCatmospheric pressure chemical ionisation interface-MS. Four of the subjects exhibited 0:1 on a molar basis and were termed . In the eleven normal converters (seven males and four females), the calculated conversion factors of 0:1 to 128 (sd 28:1 to 221 (sd 5·3):1 on a weight basis. The 52 d post-intestinal absorption conversion was estimated to be about 30 % of the total converted retinol.Keywords
This publication has 22 references indexed in Scilit:
- Vitamin A equivalence of β-carotene in a Woman as determined by a stable isotope reference methodEuropean Journal of Nutrition, 2000
- Deuterium enrichment of retinol in humans determined by gas chromatography electron capture negative chemical ionization mass spectrometryThe Journal of Nutritional Biochemistry, 1998
- [13] Atmospheric pressure chemical ionization and electron capture negative chemical ionization mass spectrometry in studying β-carotene conversion to retinol in humansMethods in Enzymology, 1997
- Teratogenicity of High Vitamin A IntakeNew England Journal of Medicine, 1995
- Serum carotenoids and retinoids in ferrets fed canthaxanthinThe Journal of Nutritional Biochemistry, 1993
- Enzymatic conversion of β-carotene into β-apo-carotenals and retinoids by human, monkey, ferret, and rat tissuesArchives of Biochemistry and Biophysics, 1991
- Carotene dioxygenase (EC1. 13. 11. 21) activity in rat intestine: effects of vitamin A deficiency and of pregnancyBritish Journal of Nutrition, 1986
- Vitamin A Metabolism and Requirements in the Human Studied with the Use of Labeled RetinolPublished by Elsevier ,1975
- Studies on the Intestinal Absorption of Radioactive β-Carotene and Vitamin A in Man: Conversion of β-carotene into vitamin AScandinavian Journal of Clinical and Laboratory Investigation, 1967
- The intestinal absorption and metabolism of vitamin A and beta-carotene in man.Journal of Clinical Investigation, 1966