Synthesis of mono- and di-functional benzyl and phenethyl derivatives containing silicon

Abstract

Dimethylbis(p-tolyl)silane was converted into the mono- or di-benzyl bromides by reaction with appropriate equivalents of N-bromosuccinimide; these were then converted into the nitriles, which were hydrolyzed to the corresponding phenylacetic acids or reduced to the phenethylamines. The mono- and di-phenethyl alcohols were prepared by reduction of the corresponding acids with lithium aluminium hydride. The dialdehyde, dimethylbis(p-formylphenyl)silane, was prepared by hydrolysis of dimethylbis(p-dibromomethylphenyl)silane.