Antagonism of prostaglandin-induced cyclic AMP accumulation in the rat anterior pituitary in vitro by somatostatin analogues
- 1 August 1976
- journal article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 32 (8), 1034-1036
- https://doi.org/10.1007/bf01933956
Abstract
The PGE2-induced cyclic AMP accumulation in the rat anterior pituitary in vitro is inhibited by [desamino1]-, [desamino1] [descarboxy14] and [d-Lys4]-somatostatin similarly to somatostatin, while the [descarboxy14]-somatostatin exhibits reduced activity; [d-Lys9]-somatostatin is ineffective at a higher concentration.Keywords
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