A BINARY MUTABILITY SYSTEM IN ESCHERICHIA COLI
- 1 May 1956
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 42 (5), 245-249
- https://doi.org/10.1073/pnas.42.5.245
Abstract
The high rate of spontaneous mutation to streptomycin resistance (S) exhibited by the K-12 substrain CS19 was shown to involve a binary mutability system. Mutations occur at or near the same S locus, but their high frequency depends upon a remotely linked factor, Mut+. The segregation of Mut+/Mut- is well defined and is consistent with a close linkage to the L (leucine) locus.This publication has 15 references indexed in Scilit:
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