STIMULATION OF MYOCARDIAL-CONTRACTILITY BY A NEW CYCLIC NUCLEOTIDE ANALOG, 8-(BENZYLTHIO)-N6-NORMAL-BUTYLADENOSINE CYCLIC 3',5'-PHOSPHATE (SQ80122)
- 1 January 1976
- journal article
- research article
- Vol. 2 (4), 307-319
Abstract
The cyclic nucleotide analog, 8-(benzylthio)-N6-n-butyladenosine cyclic 3'',5''-phosphate (SQ 80122) increases contractile force of excised cat right ventricular papillary muscle and stimulates myocardial contractility in the anesthetized dog. The inotropic action of this compound is independent of catecholamines and stimulation of .beta.-adrenergic receptors in the heart.This publication has 8 references indexed in Scilit:
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