Half-Lives of Homologous Serum Albumins in Several Species.

Abstract

The albumin half-lives determined by tracing I131 labelled homologous albumin were as follows: cow, 20.7 days; human, 15.0 days; dog, 8.2 days; rabbit, 5.7 days; and mouse, 1.2 days. The albumin half-lives are similar to the gamma globulin half-lives for the same species and apparently are dependent upon the metabolic characteristics of the host.