The amino acid sequence of wheat histone H2A(1). A core histone with a C-terminal extension

Abstract

1. The complete amino acid sequence (145 residues) of histone variant H2A₍₁₎ from wheat germ Triticum aestivum cultivar T 4 has been established from Edman degradation of large overlapping fragments. 2. The sequence of histone variant H2A₍₁₎ differs from the homologous calf histone in 61 amino acid positions. These differences include an extension of H2A₍₁₎ by 19 amino acids at its carboxyl end.