Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box
- 1 September 1989
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 341 (6240), 299-303
- https://doi.org/10.1038/341299a0
Abstract
The TATA sequence-binding factor TFIID plays a central role both in promoter activation by RNA polymerase II and other common initiation factors, and in promoter regulation by gene-specific factors. The sequence of yeast TFIID, which seems to be encoded by a single gene, contains interesting structural motifs that are possibly involved in these functions, and is similar to sequences of bacterial sigma factors.Keywords
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