New insights into the spatiotemporal localization of prothrombinase in vivo
Open Access
- 11 September 2014
- journal article
- Published by American Society of Hematology in Blood
- Vol. 124 (11), 1705-1714
- https://doi.org/10.1182/blood-2014-03-565010
Abstract
Key Points: Prothrombinase bound in the vicinity of vascular damage is distributed away from platelets and is largely found on activated endothelium. The activated endothelium plays an unexpectedly important role in supporting prothrombinase assembly and function at the site of damage.Keywords
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