Regression of Body Compositional Abnormalities of Heart Failure after Intracardiac Operations
- 1 December 1970
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 42 (6), 999-1008
- https://doi.org/10.1161/01.cir.42.6.999
Abstract
Alterations in body composition are present in patients with heart disease and congestive heart failure, and additional changes occur acutely after corrective surgery. The reversibility and time course of reversion to normal body composition have not been demonstrated. Nine patients were studied preoperatively and 2 to 4 weeks and 6 to 12 mo postoperatively. Measurements were made, using the isotope-dilution technic, of the volumes of total body water, extracellular water, plasma, and red cells, and of the amounts of total exchangeable sodium and potassium. Values were derived for body fat, indices of body cell mass, and the intracellular and extracellular distribution of water and potassium. Significant changes ( P < 0.05) occurring 2 to 4 weeks after operation were increased in total body water (8.2%), intracellular water (15.0%), exchangeable sodium (7.1%), and intracellular potassium content (7.7%), and decrease in body weight (4.6%) and body fat (21.6%); 6 to 12 mo postoperatively there was increase in exchangeable potassium (6.8%), body weight (7.8%), and decrease in exchangeable sodium (16.1%), extracellular fluid (7.8%), plasma (8.0%), and the ratio of exchangeable sodium to exchangeable potassium (23.6%). Late postoperative values were similar to predicted normal values and indicate that postoperative recovery from valvular replacement in these patients is accompanied by resolution of most of the body compositional abnormalities of heart failure.Keywords
This publication has 16 references indexed in Scilit:
- Body Composition in Heart DiseaseActa Medica Scandinavica, 2009
- Sodium-Excreting Ability Before and After Intracardiac SurgeryCirculation, 1970
- Potassium and Cardiac SurgeryThe Annals of Thoracic Surgery, 1969
- Reference Models for Clinical Studies by Isotope DilutionAnnals of Surgery, 1968
- Automated Treatment of Critically Ill Patients Following OperationAnnals of Surgery, 1968
- Effect of intracardiac operations upon congestive heart failure and body compositionThe American Journal of Cardiology, 1968
- TOTAL BODY WATER AND TOTAL EXCHANGEABLE SODIUM IN EDEMATOUS STATES DUE TO CARDIAC, RENAL OR HEPATIC DISEASE 1JCI Insight, 1956
- THE ELECTROLYTE CONTENT OF SKELETAL MUSCLE IN CONGESTIVE HEART FAILURE; A COMPARISON OF RESULTS WITH INULIN AND CHLORIDE AS REFERENCE STANDARDS FOR EXTRACELLULAR WATER 1JCI Insight, 1952
- DETERMINATION OF THE CIRCULATING RED CELL VOLUME IN MAN BY RADIOACTIVE CHROMIUM 1JCI Insight, 1950
- STUDIES OF PLASMA VOLUME USING HUMAN SERUM ALBUMIN TAGGED WITH RADIOACTIVE IODINE131JCI Insight, 1950